David B Peden Selected Research

Ozone

4/2022	Development and Application of an Open Tool for Sharing and Analyzing Integrated Clinical and Environmental Exposures Data: Asthma Use Case.
1/2020	Short course gamma tocopherol did not mitigate effects of ozone on airway inflammation in asthmatics.
12/2019	The "envirome" and what the practitioner needs to know about it.
12/2018	Low-level ozone has both respiratory and systemic effects in African American adolescents with asthma despite asthma controller therapy.
1/2016	A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation.
3/2015	SRC-mediated EGF receptor activation regulates ozone-induced interleukin 8 expression in human bronchial epithelial cells.
10/2012	Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways.
7/2011	GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozone.
7/2011	The role of oxidative stress and innate immunity in O(3) and endotoxin-induced human allergic airway disease.
5/2011	Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone.

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David B Peden Research Topics

Disease

43	Asthma (Bronchial Asthma) 04/2022 - 08/2002
39	Inflammation (Inflammations) 01/2020 - 08/2002
7	Hypersensitivity (Allergy) 02/2021 - 12/2002
5	Infections 02/2021 - 08/2002
4	Lung Diseases (Lung Disease) 03/2014 - 04/2008
2	Obesity 10/2021 - 12/2019
2	COVID-19 02/2021 - 05/2020
2	Disease Progression 12/2019 - 07/2011
2	Inhalation Burns 05/2015 - 01/2013
2	Burns 05/2015 - 01/2013
2	Pneumonia (Pneumonitis) 03/2015 - 12/2010
2	Allergic Rhinitis 10/2011 - 06/2009
2	Chronic Obstructive Pulmonary Disease (COPD) 09/2009 - 04/2008
2	Cystic Fibrosis (Mucoviscidosis) 04/2008 - 01/2006
1	Neoplasms (Cancer) 01/2022
1	Asymptomatic Infections 01/2020
1	Atopic Dermatitis (Atopic Eczema) 12/2019
1	Eosinophilia 01/2018
1	Respiratory Tract Infections (Respiratory Tract Infection) 12/2017
1	Mucositis 04/2016
1	Anaphylaxis (Anaphylactic Shock) 04/2016
1	Leukemia 04/2016
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2016
1	Virus Diseases (Viral Diseases) 10/2015
1	Drug-Related Side Effects and Adverse Reactions 05/2014
1	Lung Injury 03/2014
1	Human Influenza (Influenza) 10/2012

Drug/Important Bio-Agent (IBA)

19	OzoneIBA 04/2022 - 08/2002
15	EndotoxinsIBA 11/2019 - 08/2002
13	Environmental Pollutants (Pollutants, Environmental)IBA 12/2019 - 08/2002
10	AllergensIBA 10/2015 - 06/2006
8	Particulate MatterIBA 04/2022 - 08/2002
7	Biomarkers (Surrogate Marker)IBA 01/2021 - 04/2004
6	Air Pollutants (Pollutants, Air)IBA 01/2019 - 08/2002
5	gamma-TocopherolIBA 01/2020 - 10/2007
5	CytokinesIBA 01/2018 - 12/2002
4	SmokeIBA 12/2019 - 09/2009
4	AntioxidantsIBA 01/2018 - 10/2007
3	Biological ProductsIBA 02/2021 - 08/2002
3	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2021 - 06/2008
3	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2019 - 12/2009
3	Vitamin E FDA LinkGeneric 01/2018 - 07/2013
3	Interleukin-10 (Interleukin 10)IBA 05/2015 - 12/2010
3	InflammasomesIBA 10/2012 - 07/2011
3	ChemokinesIBA 06/2012 - 02/2006
2	Prednisone (Sone)FDA LinkGeneric 04/2022 - 10/2021
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2022 - 03/2008
2	Vehicle Emissions (Emissions, Vehicle)IBA 05/2014 - 08/2002
2	Interleukin-13IBA 05/2014 - 06/2012
2	Therapeutic UsesIBA 03/2014 - 10/2007
2	LipopolysaccharidesIBA 03/2014 - 02/2011
2	Tocopherols (Tocopherol)IBA 03/2014 - 01/2013
2	Interleukin-6 (Interleukin 6)IBA 10/2012 - 09/2002
2	Proteins (Proteins, Gene)FDA Link 08/2012 - 01/2006
2	Toll-Like Receptor 4IBA 07/2011 - 09/2010
2	Messenger RNA (mRNA)IBA 12/2010 - 06/2006
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2008 - 03/2008
2	AntigensIBA 06/2008 - 03/2008
2	HLA-DR Antigens (HLA-DR)IBA 03/2008 - 06/2006
1	IonophoresIBA 01/2022
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2022
1	ProstaglandinsIBA 01/2022
1	LeukotrienesIBA 01/2022
1	VaccinesIBA 02/2021
1	Immunoglobulin G (IgG)IBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2019
1	Nitrogen OxidesIBA 12/2019
1	Immunoglobulin E (IgE)IBA 12/2019
1	C-Reactive ProteinIBA 01/2019
1	Amyloid (Amyloid Fibrils)IBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2018
1	MucinsIBA 01/2018
1	SteroidsIBA 01/2018
1	Fibroblast Growth Factor 7 FDA Link 04/2016
1	pegaspargase (Oncaspar)FDA Link 04/2016
1	NF-E2-Related Factor 2IBA 01/2016
1	isothiocyanic acidIBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	sulforaphaneIBA 01/2016
1	Interleukin-1 (Interleukin 1)IBA 10/2015
1	ErbB Receptors (EGF Receptor)IBA 03/2015
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 02/2015
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 02/2015
1	Pharmaceutical PreparationsIBA 11/2014
1	MicroRNAs (MicroRNA)IBA 06/2014
1	montelukast (Singulair)FDA Link 05/2014
1	lebrikizumabIBA 05/2014
1	Bronchodilator Agents (Bronchodilators)IBA 05/2014
1	Antiviral Agents (Antivirals)IBA 10/2012
1	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA 08/2012
1	Interleukin-8 (Interleukin 8)IBA 08/2012
1	Small Interfering RNA (siRNA)IBA 08/2012
1	glutathione S-transferase M1IBA 08/2012
1	Chemokine CCL26IBA 06/2012
1	purineIBA 05/2011

Therapy/Procedure

10	Therapeutics 01/2022 - 10/2007
2	Artificial Respiration (Mechanical Ventilation) 05/2015 - 01/2013
1	Precision Medicine 01/2021
1	Biological Therapy 05/2020
1	Bronchial Thermoplasty 05/2014